GSK has halted all shipments of ARIXTRA Starter Kits containing the Triad For important product information, log onto Arixtra mg/ ml solution for injection, pre-filled syringe. 2. .. Detailed information on this medicinal product is available on the website of the European . Arixtra is a medicine that helps prevent blood clots from forming in the blood This medicinal product contains less than 23 mg of sodium in each dose and.
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Postoperative enoxaparin for prevention of venous thromboembolism after elective hip-replacement surgery: Prevention of VTE in nonsurgical patients: If coadministration is essential, monitor patients closely Platelet function or global clotting function tests e.
Used for extended prophylaxis i.
Available for Android and iOS devices. No specific dosage recommendations; however, careful attention to dosage directions recommended. Prevention of VTE in orthopedic surgery patients: Distributed into milk in rats; not known whether distributed into human milk. A randomized double-blind comparison. Discontinue platelet-aggregation inhibitors prior to initiation of fondaparinux 1 40 If coadministration is essential, monitor patients closely 1 Anemia, fever, nausea, edema, constipation, rash, vomiting, insomnia, increased wound drainage, hypokalemia, urinary tract infection, dizziness, purpura, hypotension, confusion, bullous eruption, urinary retention, hematoma, major bleeding, diarrhea, dyspepsia, postoperative hemorrhage, headache.
Subscribe to free Drugs. Some packaging components e.
Bounameaux, H, Perneger T. Subcutaneous fondaparinux versus intravenous unfractionated heparin in the initial treatment of pulmonary embolism. Medically reviewed on Oct 23, Risk also increased by history of traumatic or repeated epidural or spinal puncture, spinal deformity, or spinal surgery.
Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: Food and Drug Administration. Patients undergoing abdominal surgery: We comply with the HONcode standard for trustworthy health information – verify here.
Arixtra Monograph for Professionals –
A new synthetic pentasaccharide for thrombosis prevention. Active major bleeding, bacterial endocarditis, or thrombocytopenia associated with a positive in vitro test for antiplatelet antibody HIT in the presence of the drug.
Am J Health-Syst Pharm. LMWHs or fondaparinux generally preferred over heparin for initial treatment of acute venous thromboembolism; however, heparin may be preferred in patients xrixtra renal impairment.
Importance of discontinuing fondaparinux and immediately contacting a clinician if a serious allergic reaction e. Initial parenteral anticoagulants with established efficacy in patients with NSTE ACS include enoxaparin, heparin, bivalirudin only in patients managed with an early invasive strategyand fondaparinux.
The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Usual duration of therapy is 5—9 days, 1 3 4 5 6 although up to 11 days has been studied in clinical trials of orthopedic surgery.
Print this page Add to My Med List. Monitor frequently for manifestations of neurologic impairment and treat urgently if neurologic compromise noted. If PCI is performed while a patient is receiving fondaparinux, administer an additional anticoagulant with anti-factor IIa antithrombin activity prewcribing of the arlxtra of catheter thrombosis.
Evaluate the possibility of an underlying bleeding disorder before initiation of treatment. In healthy adults, distributes mainly in blood and only to a minor extent in extravascular fluid.